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This gene encodes a voltage-dependent anion channel protein that is a major component of the outer mitochondrial membrane. The encoded protein facilitates the exchange of metabolites and ions across the outer mitochondrial membrane and may regulate mitochondrial functions. This protein also forms channels in the plasma membrane and may be involved in transmembrane electron transport. Alternate splicing results in multiple transcript variants. Multiple pseudogenes of this gene are found on chromosomes 1, 2 3, 6, 9, 12, X and Y.
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|Voltage-dependent anion-selective channel protein 1, VDAC-1, hVDAC1, Outer mitochondrial membrane protein porin 1, Plasmalemmal porin, Porin 31HL, Porin 31HM, VDAC1, VDAC|
|Target/Specificity||Recombinant fusion protein containing a sequence corresponding to amino acids 1-283 of human VDAC1|
|Format||Purified polyclonal antibody supplied in PBS with 0.02% sodium azide, 50% glycerol, pH7.3|
|Reactivity||Human, Mouse, Rat|
|Application||WB 1:500 - 1:2000|
|IHC 1:50 - 1:200|
|IF 1:50 - 1:200|
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