In vertebrates 3 main groups of actin isoforms, alpha, beta and gamma have been identified. Alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. Beta and gamma actins coexist in most cell types as components of the cyto-skeleton and as mediators of internal cell motility. Beta actins are highly conserved proteins that are involved in cell motility, structure and integrity. Beta actins are cytoplasmic proteins. Anti-Actin is a loading control antibody and is critical for the correct interpretation of your western blot. Beta-Actin Loading Control Antibody is used to normalize the levels of protein detected by confirming that protein loading is uniform across the gel.
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|Other Names||beta actin, ß actin, anti-beta actin|
|Target/Specificity||beta-Actin Loading Control Antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 359-368 of Human beta Actin|
|Format||Purified polyclonal antibody supplied in 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2|
|Reactivity||Mouse, Rat, Human, Monkey, Sheep, Bovine, Goat, Guinea Pig, Swine, Hamste|
|Application||ELISA : 1:10,000 - 1:40,000|
|IF : 1:500 - 1:2,000|
|Western Blot : 1:1,000 - 1:4,000|
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