The Xpert Phosphatase Inhibitor Cocktail Solution(100X)
is a mixture of several inhibitors to prevent valuable
proteins from dephospholylation. Phosphorylation and
dephosphorylation is a molecular on/off switch that regulates
a number of key biological pathways within the cell,
including signal transduction, cell division, and apoptosis.
The Xpert Phosphatase Inhibitor Cocktail preserves
phosphorylation of proteins in cell lysates and tissue
extracts. The cocktail contains a mixture of four
phosphatase inhibitors of broad specificity, including
sodium fluoride, sodium orthovanadate, sodium
pyrophosphate and sodium glycerophosphate.
Unlike other commercially available phosphatase
inhibitor cocktails which protect against either
Ser/Thr phosphatases or protein tyrosine
The Xpert Phosphatase Inhibitor Cocktail protects
phosphoproteins from both families of phosphatases.
Conveniently packaged in a 100X format, the cocktail
is stable at 4°C and is compatible with common protein
assays, including the BCA Protein Assay and Bradford-
based assays such as Coomassie.