Search term Growth Factor has been found in the following products: 155

Growth Factor

ADAM10, Human Recombinant Protein, CG1002

  • ADAM10 Human Recombinant
  • Lyophilized Powder
  • Greater than 95% by SDS-PAGE
  • ADAM Metallopeptidase Domain 10
Collapse Store at -20℃
Cat No Size Price
CG1002-002 2 ug $ 125.00 Add to cart
CG1002-010 10 ug $ 185.00 Add to cart
Source Escherichia Coli.
Formulation The ADAM10 solution contains 20mM Tris (pH 8), 1mM EDTA and 50% Glycerol.
Purity Greater than 95.0% as determined by SDS-PAGE.
Stability Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.
ADAM10 is part of the ADAM family which are cell surface proteins with a distinctive structure possessing both potential adhesion and protease domains. ADAM10 cleaves many proteins including TNF-alpha and E-cadherin. ADAM10 cleaves the membrane-bound precursor of tnf-alpha at 76- ala-|-val-77 to its mature soluble form. ADAM10 is in charge for the proteolytic release of several other cell-surface proteins, including ephrin-a2 and for constitutive and regulated alpha-secretase cleavage of amyloid precursor protein. ADAM10 is involved in the normal cleavage of the cellular prion protein. ADAM10 is involved in the cleavage of the adhesion molecule l1 at the cell surface and in the release of membrane vesicles, suggesting a vesicle-based protease activity. ADAM10 controls the proteolytic processing of notch and mediates lateral inhibition during neurogenesis.