Search term Cell/Tissue Culture has been found in the following products: 280

Cell/Tissue Culture

Aprotinin, From Bovine Lung, CA181

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Description
Aprotinin inhibits the activity of several proteolytic enzymes such as chymotrypsin, kallikrein, plasmin and trypsin. Aprotinin is present in blood and in most tissues, with a high concentration in lung. Aprotinin inhibits pro-inflammatory cytokine release and maintains glycoprotein homeostasis. In platelets, aprotinin reduces glycoprotein loss (e.g., GpIb, GpIIb/IIIa), while in granulocytes it prevents the expression of pro-inflammatory adhesive glycoproteins (e.g., CD11b).

Aprotinin is a natural proteinase inhibitor polypeptide consisting of fifty-eight amino acids arranged in a single polypeptide chain, cross-linked by three disulfide bridges and having a molecular mass of 6512.


Source
Bovine Lung

 

Physical Description
Sterile Filtered White lyophilized (freeze-dried) powder


Formulation
The protein (1mg/ml) was lyophilized with no additives 


Solubility
It is recommended to reconstitute the lyophilized Aprotinin in sterile water not less than 100ug/ml, which can then be further diluted to other aqueous solutions. 
.

Store at -20oC
; Lyophilized form stable at room temperature for 3 weeks,
should be stored desiccated below -20oC .

Upon reconstitution, should be stored at 4oC between 2-7 days
and for future use below -20oC.