Search term Biomolecules has been found in the following products: 25

Biomolecules

Cyclosporin A, >99% , BC020

  • CAS NO : 59865-13-3
  • Formula : C62H111N11O12
  • MW : 1202.61
  • Purity : ≥99%
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Cat No Size Price
BC020-101 1 g $ 108.00 Add to cart
BC020-105 5 g $ 225.00 Add to cart
BC020-110 10 g $ 385.00 Add to cart
IC50 7 nM
Targets Calcineurin
Solubility 100 mg/mL warmed (83.15 mM) in DMSO
A fungal metabolite possessing potent immunosuppressive properties. It inhibits the T-cell receptor signal transduction pathway via the formation of cyclosporin A−cyclophilin complex that inhibits calcineurin (protein phosphatase 2B). Inhibits nitric oxide synthesis induced by interleukin 1α, lipopolysaccharides and TNFα. Can block cytochrome c release from mitochondria.