Search term Biomolecules has been found in the following products: 25

Biomolecules

Bisindolylmaleimide I

  • CAS NO : 133052-90-1
  • Formula : C₂₅H₂₄N₄O₂
  • MW : 412.5
  • Purity : ≥95%
Collapse Store at -20℃
Cat No Size Price
BC006-005 5 mg $ 155.00 Add to cart
BC006-010 10 mg $ 245.00 Add to cart
BC006-025 25 mg $ 510.00 Add to cart
IC50 20 nM, 17 nM, 16 nM, and 20 nM for PKCα, PKCβI, PKCβII, and PKCγ
Targets PKCα, PKCβ1, PKCβ2, PKCγ
Solubility 82 mg/mL (198.79 mM) in DMSO
Other Name BIM I
GF 109203X
Gö 6850
Bisindolylmaleimide I (GF109203X) is a potent PKC inhibitor with IC50 of 20 nM, 17 nM, 16 nM, and 20 nM for PKCα, PKCβI, PKCβII, and PKCγ in cell-free assays, respectively, showing more than 3000-fold selectivity for PKC as compared to EGFR, PDGFR and insulin receptor.