Search term Antibodies has been found in the following products: 44

Antibodies

AffiSelect GAPDH Loading Control Antibody , A0039

  • Purified Rabbit Polyclonal Antibody
  • Rabbit IgG
  • GAPDH Antibody
Collapse Store at -20℃
Cat No Size Price
A0039-001 100ug $ 325.00 Add to cart
Other Names Glyceraldehyde-3-phosphate dehydrogenase, GAPDH, Peptidyl-cysteine S-nitrosylase GAPDH, 2699-, GAPDH, GAPD
Target/Specificity Recombinant fusion protein containing a sequence corresponding to amino acids 1-335 of human GAPDH
Format Purified polyclonal antibody supplied in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Host Rabbit
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Application WB : 1:1000 - 1:10000
IHC :1:50 - 1:100
IF : 1:20 - 1:50

Glyceraldehyde-3-phosphate dehydrogenase (GAPDH),also called uracil DNA glycosylase, catalyzes the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate in the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD), an important energy-yielding step in carbohydrate metabolis.


While GAPDH has long been recognized as  playing an integral role in glycolysis, additional functions of GAPDH include acting as an uracil DNA glycosylase, activating transcription, binding RNA and involvement in nuclear RNA export, DNA replication and DNA repair. Expression of GAPDH is upregulated in liver, lung and prostate cancers. GAPDH translocates to the nucleus during apoptosis. GAPDH complexes with neuronal proteins implicated in human neurodegenerative disorders including the β-Amyloid precursor, Huntingtin and other triplet repeat neuronal disorder proteins.